RESUMO
The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. The average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. The statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study.
Assuntos
Fármacos Dermatológicos/uso terapêutico , Isotretinoína/uso terapêutico , Doenças das Glândulas Sebáceas/tratamento farmacológico , Glândulas Sebáceas/patologia , Adulto , Feminino , Humanos , Hiperplasia/tratamento farmacológico , Pele/efeitos dos fármacos , Estatísticas não Paramétricas , Fatores de Tempo , Resultado do TratamentoRESUMO
The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. The average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. The statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study.
Assuntos
Adulto , Feminino , Humanos , Fármacos Dermatológicos/uso terapêutico , Isotretinoína/uso terapêutico , Doenças das Glândulas Sebáceas/tratamento farmacológico , Glândulas Sebáceas/patologia , Hiperplasia/tratamento farmacológico , Estatísticas não Paramétricas , Pele/efeitos dos fármacos , Fatores de Tempo , Resultado do TratamentoRESUMO
Este relato de caso trata de uma paciente com hipotireoidismo, que apresentou tumor ovariano raro, de tecido tireoidiano, denominado Struma ovarii. Em análise da literatura, somente 5% dos casos associa-se a hipertireoidismo, não havendo relatos de associação a hipotireoidismo. Foram demonstradas imagens de ultrassonografia, laparoscopia e histologia do tumor, e realizadas comparações clínicas com as características previamente descritas sobre esse tipo de tumor
This case report is about a patient with hypothyroidism who presented a rare ovarian tumor containing thyroid tissue, known as struma ovarii. According to the literature, only 5% of the cases are associated with hyperthyroidism and there are no reports of an association with hypothyroidism. Ultrasound, laparoscopic and histological images of the tumor were compared with the characteristics of this type of tumor described in the literature
